Obstetrics and pregnancy care
Non-invasive prenatal testing (NIPT)
Maternal blood screening of cell-free DNA to estimate the risk of selected fetal chromosomal conditions.
Explained in clear language
What it is
It analyses placental DNA fragments circulating in maternal blood. It has strong screening performance for some trisomies but does not replace diagnostic testing.
How it is performed
- 1
Individual assessment and indication
- 2
Explanation, alternatives and consent
- 3
Procedure with appropriate safeguards
- 4
Results, aftercare and follow-up
Askabide visual archive
The procedure, also explained through images
The photographs come from Askabide’s clinical and “more information” sections. They have been selected by clinical area to support the explanation; not every image is a literal representation of each manoeuvre and none replaces an individual medical explanation.
Assessment and indication
The indication is decided after listening to the reason for attending, reviewing history and explaining the clinical question that needs to be answered.
How it is carried out
The technique, sample collection, device or intervention is adapted to the individual situation and explained before it starts.
Results and follow-up
The result is not interpreted in isolation: symptoms, examination, age, history and complementary tests are considered together.
Clinical interpretation
What is important to understand before deciding
What it can contribute
This procedure addresses a specific clinical question. Its usefulness depends on the indication, timing and technique being appropriate for your situation.
What it cannot determine on its own
No test or procedure should be interpreted outside its clinical context. A normal result does not dismiss persistent symptoms, and an abnormal finding does not automatically mean serious disease.
What happens afterwards
Depending on the result, the next step may be discharge, observation, repeat testing, further assessment or treatment. The plan is explained before the episode is considered complete.
Expanded information
Questions we answer during the consultation
The technical information on this page helps you prepare for the consultation. The final decision is made after assessing your circumstances and confirming that the likely benefit outweighs the risk.
Why does the pregnancy week matter so much?
Each test has a window in which it answers a particular question most accurately. Gestational age changes what can be seen, measured and interpreted.
Does a normal result rule out every problem?
No. Each test has a defined scope and limitations. A reassuring result reduces certain risks but cannot guarantee the absence of every possible condition.
What happens if an unexpected finding appears?
It is explained clearly, the need for confirmation is assessed, and the next step may be monitoring, an additional test, referral or specialist counselling.
What it is used for and when
- Prenatal screening after information and consent.
- Intermediate- or high-risk result from previous screening.
- Situations where improved risk estimation is desired without an initial invasive test.
How it is performed
Maternal blood is collected from an appropriate gestation. The laboratory reports low or high risk and possible limitations such as insufficient fetal fraction.
Preparation
You will be told whether fasting, a specific time or a particular day of the cycle is needed. Do not stop medication without advice.
Tell the team beforehand if pregnancy is possible, you take anticoagulants, have allergies, active infection or a relevant medical condition. Specific instructions take priority over the general information on this page.
After the procedure
The laboratory or pathology department needs time to process the sample. You will be told how and when results will be given and what follow-up may be needed.
Risks, limitations and alternatives
It is a screening test, not a diagnosis. A high-risk or discordant result requires counselling and usually confirmation by chorionic villus sampling or amniocentesis before clinical decisions.
Clinical judgement and evidence
In obstetrics it is essential to distinguish screening from diagnosis. Screening estimates risk; a high-risk result may need diagnostic confirmation before clinical decisions are made.
Related procedures
Askabide Klinika
Not sure which procedure you need?
You do not need to choose a test on your own. Tell us what concerns you and the team will guide you after assessing your situation.